Heading further west on 66 we reach Sante Fe, NM..Santa Fe Loop of Route 66 The original alignment of Route 66 between 1926 and 1937 went from Santa Rosa to Albuquerque via Romeroville, Bernal, Pecos, Santa Fe, Santo Domingo, Algodones and Bernalillo. It was bypassed in 1937 with the "Santa Fe Cut Off" which shortened the alignment via Moriarty. Santa Fe combines Spanish Colonial and Native American Pueblo culture and history. Arts, crafts, food and amazing outdoors on an iconic Route 66 city. Downtown Sante Fe, NM.